As of 31 March 2025, 20 cannabis cultivation licences have been issued in the Western Cape. This represents 21.05% of the total cannabis cultivation licences issued in South Africa.
| Company | Date Issued | Expiry Date |
|---|---|---|
| Alphaplant Pharmaceutical (Pty) Ltd | 6 January 2022 | 6 January 2027 |
| Beyond Buds (Pty) Ltd | 13 September 2021 | 13 September 2026 |
| Biogeist (Pty) Ltd | 6 May 2021 | 6 May 2026 |
| Budbrothers (Pty) Ltd | 27 February 2025 | 27 February 2030 |
| CapeBud (Pty) Ltd | 17 May 2022 | 17 May 2027 |
| Chroni Co Holdings (Pty) Ltd | 24 August 2021 | 24 August 2026 |
| Cloetes Boerdery (Pty) Ltd | 22 March 2024 | 22 March 2029 |
| Craft Horticulture (Pty) Ltd | 15 February 2022 | 15 February 2027 |
| Felbridge (Pty) Ltd | 26 October 2020 | 26 October 2025 |
| Green Rocket | 22 July 2024 | 22 July 2029 |
| Igrow Consulting (Pty) Ltd | 30 May 2022 | 30 May 2027 |
| Karoo Bioscience (Pty) Ltd | 23 May 2022 | 23 May 2027 |
| MedReleaf (Pty) Ltd | 2 September 2021 | 2 September 2026 |
| Montagu Cannabis Company (Pty) Ltd | 4 June 2024 | 4 June 2029 |
| Perfect Plants (Pty) Ltd | 7 January 2022 | 7 January 2027 |
| Sativa Grow (Pty) Ltd | 10 November 2022 | 10 November 2027 |
| Seven Blade Medical (Pty) Ltd | 9 September 2021 | 9 September 2026 |
| Simonshoogte (Pty) Ltd | 19 July 2023 | 19 July 2028 |
| Uncle Rooneys (Pty) Ltd | 23 December 2021 | 23 December 2026 |
| White Lion Holdings (Pty) Ltd | 24 February 2022 | 24 February 2027 |